Monthly Archives: April 2011

30 04, 2011
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    Paraoxonases as potential antibiofilm agents: their relationship with quorum-sensing signals in Gram-negative bacteria.

Paraoxonases as potential antibiofilm agents: their relationship with quorum-sensing signals in Gram-negative bacteria.

By |April 30th, 2011|Publicacions|0 Comments|

Camps J, Pujol I, Ballester F, Joven J, Simó JM.

Source
Centre de Recerca Biomédica, Laboratori de Microbiologia, and Laboratori de Referéncia de Catalunya, Hospital Universitari de Sant Joan, Institut d’Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain. [email protected]

Abstract

The property of many bacteria to form biofilms constitutes a major health problem. Bacteria living in biofilms have a very high resistance to antibiotics. Biofilms may develop at a certain locations with the participation of secreted molecules, termed quorum-sensing signals, when a sufficient density of bacterial growth occurs. In Gram-negative bacteria, acyl homoserine lactones (AHL) have been identified as major quorum-sensing signals. The paraoxonases (PONs) constitute a family of enzymes comprising 3 members (PON1, PON2, and PON3) that have lactonase activity and are able to […]

14 04, 2011

Judit, con los premios Nobel

By |April 14th, 2011|Notícies|0 Comments|

Hace ya dos años que Judit Marsillach defendió su tesis y obtuvo el grado de Doctora. Poco después, dejó el CRB para comenzar su travesía de post-doc en Seattle donde está desde hace año y medio en Department of Genome Sciences and Medicine (division of Medical Genetics) de la University of Washington.

Bajo la dirección del Dr. Clement E Furlong, Judit trabaja en los proyectos Paraoxonasa-1 recombinante humana: cristalización y estudio de el efecto terapéutico en hepatopatías y sensibilitat a organofosforados, Biomarcadores de exposición y sensibilidad a insecticidas organofosforados y Estructura y función de la paraoxonasa-1 humana y sus polimorfismos.

A raíz de un póster que Judit presentó en el Walter E. Washington Convention Center de Washington, fué invitada, junto con […]

13 04, 2011

Noticia en el Diari de Tarragona, ¡y con portada!

By |April 13th, 2011|Notícies|0 Comments|

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5 04, 2011

Vales lo que publicas

By |April 5th, 2011|Notícies|0 Comments|

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1 04, 2011

Gerosuppressant metformin: less is more

By |April 1st, 2011|Publicacions|0 Comments|

Menendez JA, Cufí S, Oliveras-Ferraros C, Vellon L, Joven J, Vazquez-Martin A.

Source
Catalan Institute of Oncology, Girona, Catalonia, Spain. [email protected]

Comment on

If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice. [Aging (Albany NY). 2011]

PMID:21483040[PubMed – indexed for MEDLINE] PMCID:PMC3117449