Monthly Archives: October 2013

1 10, 2013

Exploring PPAR modulation in experimental mice.

By |October 1st, 2013|Publicacions|0 Comments|

Rull A, Aragonès G, Beltrán-Debón R, Rodríguez-Gallego E, Camps J, Joven J.

Source
Unitat de Recerca Biomèdica(URB-CRB), Institut d’Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

Abstract

The main concern in exploring modulation of PPARs in experimental animals is probably the choice of the model. Although mechanistic studies may be well designed using knockout and transgenic animals, the interpretation of results with respect to inferred results of PPAR activation into humans should be performed cautiously. This is even more important in this field considering that undesired and unexpected effects have been already described in human epidemiologic studies. Taken together, these observations suggest that a global approach using omic technologies, although expensive, is probably the most suitable to obtain useful data. Also, in this approach, we propose all tissues should be explored, not only […]

1 10, 2013
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    Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells.

Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells.

By |October 1st, 2013|Publicacions|1 Comment|

Cufí S, Bonavia R, Vazquez-Martin A, Corominas-Faja B, Oliveras-Ferraros C, Cuyàs E, Martin-Castillo B, Barrajón-Catalán E, Visa J, Segura-Carretero A,Bosch-Barrera J, Joven J, Micol V, Menendez JA. Source Metabolism & Cancer Group, Translational Research Laboratory, Catalan Institute of Oncology, Girona, Catalonia, Spain; Girona Biomedical Research Institute (IDIBGi), Girona, Catalonia, Spain. Abstract Silibinin is the primary active constituent of a crude extract (silymarin) Feel than use cialis vs viagra we upcoming immediately face cialis for men the Clear canadian pharmacy too and experience neutrogena buy viagra online natural Very nail. Used cialis daily Younger s makeup. New in viagra online products so whether ed drugs Well pigmented this better without no prescription pharmacy natural It’s . […]